Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables cyclin binding activity; cyclin-dependent protein serine/threonine kinase activity; and magnesium ion binding activity. Involved in positive regulation of cell population proliferation. Acts upstream of or within G1/S transition of mitotic cell cycle; potassium ion transport; and regulation of nucleobase-containing compound metabolic process. Located in chromosome and nucleus. Part of cyclin-dependent protein kinase holoenzyme complex and transcription regulator complex. Is expressed in several structures, including brain; branchial arch; ear; integumental system; and limb. Human ortholog(s) of this gene implicated in prostate cancer and renal cell carcinoma. Orthologous to human CDK2 (cyclin dependent kinase 2).