Automated description from the Alliance of Genome Resources
Predicted to have ephrin receptor activity. Involved in several processes, including circulatory system development; positive regulation of T cell costimulation; and positive regulation of aorta morphogenesis. Predicted to localize to the integral component of plasma membrane and receptor complex. Used to study cystic kidney disease. Human ortholog(s) of this gene implicated in hereditary lymphedema. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Orthologous to human EPHB4 (EPH receptor B4).