Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables transcription coactivator activity and transcription corepressor activity. Involved in cell migration and maintenance of cell polarity. Acts upstream of or within several processes, including determination of adult lifespan; male gonad development; and negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Human ortholog(s) of this gene implicated in dentatorubral-pallidoluysian atrophy and schizophrenia. Orthologous to human ATN1 (atrophin 1).