Automated description from the Alliance of Genome Resources
Exhibits extracellular matrix structural constituent. Involved in glomerular basement membrane development. Localizes to the collagen type IV trimer. Used to study autosomal recessive Alport syndrome. Human ortholog(s) of this gene implicated in autosomal recessive Alport syndrome and end stage renal failure. Is expressed in glomerular tuft and testis. Orthologous to human COL4A4 (collagen type IV alpha 4 chain).