Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits Rac GTPase binding activity and actin binding activity. Predicted to contribute to Rac guanyl-nucleotide exchange factor activity. Involved in several processes, including Rac protein signal transduction; actin cytoskeleton organization; and barbed-end actin filament capping. Localizes to several cellular components, including NMDA selective glutamate receptor complex; ruffle membrane; and stereocilium tip. Is expressed in several structures, including adrenal gland; alimentary system; bone; brain; and metanephros. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 102. Orthologous to human EPS8 (epidermal growth factor receptor pathway substrate 8).