Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and transcription coregulator activity. Involved in several processes, including animal organ development; nervous system development; and regulation of transcription by RNA polymerase II. Localizes to the nucleus. Used to study orofacial cleft. Human ortholog(s) of this gene implicated in branchiooculofacial syndrome. Is expressed in several structures, including branchial arch; genitourinary system; limb; nervous system; and sensory organ. Orthologous to human TFAP2A (transcription factor AP-2 alpha).