Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable ATP hydrolysis activity; P-type calcium transporter activity; and PDZ domain binding activity. Involved in several processes, including positive regulation of bone mineralization; regulation of cytosolic calcium ion concentration; and regulation of vascular associated smooth muscle contraction. Located in several cellular components, including basolateral plasma membrane; immunological synapse; and synaptic vesicle membrane. Is active in glutamatergic synapse and photoreceptor ribbon synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Used to study chromosome 3-linked frontotemporal dementia and frontotemporal dementia. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human ATP2B1 (ATPase plasma membrane Ca2+ transporting 1).