Automated description from the Alliance of Genome Resources (Release 5.2.0)
Enables several functions, including PDZ domain binding activity; transforming growth factor beta binding activity; and transforming growth factor beta receptor activity. Involved in several processes, including definitive erythrocyte differentiation; heart development; and transmembrane receptor protein serine/threonine kinase signaling pathway. Acts upstream of or within several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and vasculogenesis. Located in cell surface and endoplasmic reticulum. Is expressed in several structures, including brain; early conceptus; heart; lower jaw; and ovary. Orthologous to human TGFBR3 (transforming growth factor beta receptor 3).