Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits microtubule binding activity and protein homodimerization activity. Involved in several processes, including cytoplasmic microtubule organization; regulation of microtubule polymerization or depolymerization; and retrograde axonal transport. Localizes to several cellular components, including cytoskeleton; focal adhesion; and sarcomere. Predicted to colocalize with intermediate filament. Is expressed in several structures, including alimentary system; nervous system; olfactory epithelium; retina nuclear layer; and skin. Used to study hereditary sensory and autonomic neuropathy type 6 and hereditary sensory neuropathy. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 6. Orthologous to human DST (dystonin).