Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables cannabinoid receptor activity. Involved in cannabinoid signaling pathway; regulation of presynaptic cytosolic calcium ion concentration; and trans-synaptic signaling by endocannabinoid. Acts upstream of or within axonal fasciculation and glucose homeostasis. Located in growth cone and presynaptic membrane. Is active in GABA-ergic synapse; glutamatergic synapse; and mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in obesity; schizophrenia; and type 2 diabetes mellitus. Orthologous to human CNR1 (cannabinoid receptor 1).