Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits guanyl-nucleotide exchange factor activity. Involved in several processes, including activation of GTPase activity; negative regulation of signal transduction; and platelet-derived growth factor receptor signaling pathway. Predicted to localize to several cellular components, including cytoplasmic vesicle; intracellular membrane-bounded organelle; and perinuclear region of cytoplasm. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; and liver. Orthologous to human RAPGEF1 (Rap guanine nucleotide exchange factor 1).