Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits protein kinase binding activity and protein serine/threonine kinase activity. Involved in response to lipopolysaccharide and toll-like receptor signaling pathway. Predicted to localize to cytoplasm and nucleus. Used to study Coffin-Lowry syndrome. Human ortholog(s) of this gene implicated in Coffin-Lowry syndrome; intellectual disability; and non-syndromic X-linked intellectual disability. Is expressed in several structures, including alimentary system; blastocyst; branchial arch; central nervous system; and eye. Orthologous to human RPS6KA3 (ribosomal protein S6 kinase A3).