Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits damaged DNA binding activity and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including regulation of gene expression, epigenetic; regulation of histone modification; and regulation of nucleobase-containing compound metabolic process. Localizes to condensed nuclear chromosome and cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Used to study breast cancer. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia; cervix uteri carcinoma in situ; colon cancer; hereditary breast ovarian cancer syndrome; and reproductive organ cancer (multiple). Orthologous to human BRCA1 (BRCA1 DNA repair associated).