Automated description from the Alliance of Genome Resources
Exhibits damaged DNA binding activity and transcription regulatory region DNA binding activity. Involved in several processes, including mitotic G2/M transition checkpoint; regulation of gene expression; and regulation of histone modification. Localizes to the condensed nuclear chromosome and cytoplasm. Used to study breast cancer. Human ortholog(s) of this gene implicated in several diseases, including cervix uteri carcinoma in situ; colon cancer; hereditary breast ovarian cancer syndrome; reproductive organ cancer (multiple); and urinary bladder cancer. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human BRCA1 (BRCA1 DNA repair associated).