Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; proline-rich region binding activity; and transcription coactivator activity. Involved in several processes, including cardiac muscle tissue regeneration; interleukin-6-mediated signaling pathway; and positive regulation of cardiac muscle cell proliferation. Acts upstream of or within several processes, including regulation of epithelial cell differentiation; regulation of epithelial cell proliferation; and tube morphogenesis. Located in several cellular components, including cell-cell junction; cytosol; and female germ cell nucleus. Part of TEAD-YAP complex. Is expressed in several structures, including brain; early conceptus; eye; jaw; and ovary. Used to study cone dystrophy. Human ortholog(s) of this gene implicated in uveal coloboma-cleft lip and palate-intellectual disability. Orthologous to human YAP1 (Yes1 associated transcriptional regulator).