Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits chromatin binding activity. Involved in cellular response to leukemia inhibitory factor and cellular response to retinoic acid. Localizes to nuclear body and sex chromatin. Used to study dilated cardiomyopathy and tetralogy of Fallot. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 11. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; nervous system; and sensory organ. Orthologous to human PHC1 (polyhomeotic homolog 1).