Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; protein homodimerization activity; and transcription corepressor binding activity. Involved in several processes, including hemopoiesis; mesonephros development; and regulation of hemopoiesis. Acts upstream of or within several processes, including limb morphogenesis; male germ-line stem cell asymmetric division; and regulation of DNA-templated transcription. Located in male germ cell nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human ZBTB16 (zinc finger and BTB domain containing 16).