Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity and N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity. Involved in purine ribonucleoside monophosphate biosynthetic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in adenylosuccinase lyase deficiency. Orthologous to human ADSL (adenylosuccinate lyase).