Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA-binding transcription factor activity. Involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; cell surface receptor signaling pathway; and negative regulation of macrophage fusion. Localizes to cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and skeletal musculature. Used to study breast cancer and severe acute respiratory syndrome. Human ortholog(s) of this gene implicated in breast carcinoma; primary immunodeficiency disease; and prostate adenocarcinoma. Orthologous to human STAT1 (signal transducer and activator of transcription 1).