Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; protein homodimerization activity; and protein kinase binding activity. Involved in several processes, including cellular response to hormone stimulus; neurogenesis; and regulation of nucleobase-containing compound metabolic process. Localizes to the cytoplasm; nuclear transcription factor complex; and plasma membrane. Used to study colorectal cancer; hyper IgE recurrent infection syndrome 1; inflammatory bowel disease; peripartum cardiomyopathy; and psoriasis. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; carcinoma (multiple); hyper IgE recurrent infection syndrome 1; inflammatory bowel disease (multiple); and psoriatic arthritis. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hindlimb long bone. Orthologous to human STAT3 (signal transducer and activator of transcription 3).