Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables ephrin receptor binding activity. Acts upstream of or within several processes, including axon guidance; neural crest cell migration; and positive regulation of T cell activation. Located in cytoplasm; membrane raft; and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study craniofrontonasal syndrome. Human ortholog(s) of this gene implicated in craniofrontonasal syndrome and dysostosis. Orthologous to human EFNB1 (ephrin B1).