Automated description from the Alliance of Genome Resources (Release 3.1.1)
Contributes to laminin binding activity. Involved in blood vessel morphogenesis; cell adhesion; and cell migration. Localizes to several cellular components, including integrin alpha7-beta1 complex; muscle tendon junction; and sarcolemma. Is expressed in several structures, including alimentary system; central nervous system; heart; metanephros; and skeletal musculature. Used to study congenital muscular dystrophy due to integrin alpha-7 deficiency. Human ortholog(s) of this gene implicated in Duchenne muscular dystrophy; congenital muscular dystrophy due to integrin alpha-7 deficiency; and muscular disease. Orthologous to human ITGA7 (integrin subunit alpha 7).