Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including ABC-type transporter activity; efflux transmembrane transporter activity; and glutathione transmembrane transporter activity. Involved in several processes, including cellular response to amyloid-beta; cobalamin transport; and leukotriene transport. Located in plasma membrane. Is active in basal plasma membrane. Is expressed in several structures, including embryo mesenchyme; genitourinary system; hemolymphoid system; nervous system; and nose. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 77 and chronic obstructive pulmonary disease. Orthologous to human ABCC1 (ATP binding cassette subfamily C member 1 (ABCC1 blood group)).