Automated description from the Alliance of Genome Resources
Exhibits cytokine activity and frizzled binding activity. Involved in several processes, including Norrin signaling pathway; regulation of transcription, DNA-templated; and retina vasculature morphogenesis in camera-type eye. Localizes to the collagen-containing extracellular matrix. Used to study Norrie disease and exudative vitreoretinopathy. Human ortholog(s) of this gene implicated in Norrie disease; exudative vitreoretinopathy; and retinopathy of prematurity. Orthologous to human NDP (norrin cystine knot growth factor NDP).