Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables HMG box domain binding activity and sequence-specific DNA binding activity. Involved in several processes, including metanephric nephron epithelium development; negative regulation of apoptotic process; and regulation of DNA-templated transcription. Acts upstream of or within several processes, including forebrain development; positive regulation of transcription by RNA polymerase II; and urea transmembrane transport. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; phalanx; and sensory organ. Orthologous to human POU3F3 (POU class 3 homeobox 3).