Automated description from the Alliance of Genome Resources
Exhibits RNA polymerase II activating transcription factor binding activity; RNA polymerase II distal enhancer sequence-specific DNA binding activity; and RNA polymerase II transcription factor binding activity. Involved in several processes, including negative regulation of neuron differentiation; regulation of gene expression; and somite rostral/caudal axis specification. Localizes to the nuclear chromatin. Used to study spondylocostal dysostosis. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Orthologous to human TBX6 (T-box 6).