Automated description from the Alliance of Genome Resources
Exhibits NADH dehydrogenase activity. Predicted to be involved in ATP synthesis coupled electron transport. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and MELAS syndrome. Is expressed in central nervous system; heart; liver; metanephros; and retina. Orthologous to human MT-ND5 (mitochondrially encoded NADH dehydrogenase 5).