Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits metalloendopeptidase activity. Involved in several processes, including chondrocyte proliferation; positive regulation of cell differentiation; and skeletal system morphogenesis. Predicted to localize to several cellular components, including extracellular space; intermediate filament cytoskeleton; and macropinosome. Is expressed in several structures, including bone; hindlimb mesenchyme; midbrain mantle layer; perichondrium; and reproductive system. Used to study rheumatoid arthritis. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human MMP14 (matrix metallopeptidase 14).