Automated description from the Alliance of Genome Resources (Release 5.2.2)
Predicted to enable signaling receptor binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of megakaryocyte differentiation; and thrombopoietin-mediated signaling pathway. Acts upstream of or within myeloid cell differentiation. Predicted to be located in extracellular space. Predicted to be active in extracellular region. Is expressed in several structures, including brain; gut; male reproductive gland or organ; olfactory epithelium; and yolk sac. Human ortholog(s) of this gene implicated in aplastic anemia; essential thrombocythemia; and thrombocytosis. Orthologous to human THPO (thrombopoietin).