Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables G protein-coupled receptor activity; G-protein alpha-subunit binding activity; and G-protein beta-subunit binding activity. Involved in several processes, including negative regulation of renin secretion into blood stream; positive regulation of intracellular signal transduction; and trans-synaptic signaling by endocannabinoid, modulating synaptic transmission. Acts upstream of or within several processes, including dendritic cell homeostasis; regulation of interleukin-1 beta production; and thrombin-activated receptor signaling pathway. Predicted to be located in several cellular components, including endosome; platelet dense tubular network; and postsynaptic membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and lung. Orthologous to human F2R (coagulation factor II thrombin receptor).