Glossary:Congenic Strain

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Glossary Term

Congenic Strain

Definition

An inbred strain of mouse that contains a small genetic region (ideally a single gene) from another strain, but which is otherwise identical to the original inbred strain. Congenic strains are derived by backcrossing to a parental inbred strain for at least ten generations while selecting for heterozygosity at a particular locus. A.BY-H2^b H2-T18b/SnJ is a congenic strain.
See also the Rules for Nomenclature of Mouse and Rat Strains.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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