|
Symbol Name ID |
Lamb2
laminin, beta 2 MGI:99916 |
| Darker colors indicate more annotations |
| Human Phenotypes | Retinal hemorrhage |
Retinal vascular tortuosity |
Posterior lenticonus |
Cataract |
Microcoria |
Hypoplasia of the iris |
Rieger anomaly |
Uveal ectropion |
Macular hypoplasia |
Retinal detachment |
Hypopigmentation of the fundus |
Remnants of the hyaloid vascular system |
Hypoplasia of the ciliary body |
Microphthalmia |
Strabismus |
Nystagmus |
Myopia |
High myopia |
Blindness |
Open angle glaucoma |
| Disease(s) Associated with LAMB2 | ||||||||||||||||||||
| nephrotic syndrome type 5 | ||||||||||||||||||||
| Pierson syndrome | ||||||||||||||||||||
| primary open angle glaucoma |
| Mouse Phenotypes | increased retina apoptosis |
abnormal Muller cell morphology |
decreased amacrine cell number |
abnormal amacrine cell morphology |
abnormal retina photoreceptor morphology |
short photoreceptor inner segment |
short photoreceptor outer segment |
abnormal retina rod cell morphology |
abnormal retina development |
abnormal retina morphology |
abnormal retina inner limiting membrane morphology |
abnormal retina outer plexiform layer morphology |
decreased total retina thickness |
abnormal eye physiology |
abnormal eye electrophysiology |
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| Availability | Mouse Genotype | |||||||||||||||
| Lamb2tm1Jrs/Lamb2tm1Jrs | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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