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Symbol
Name
ID
Fgf8
fibroblast growth factor 8
MGI:99604
Phenotype annotations related to skeleton
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Delayed skeletal maturation
Disease(s) Associated with FGF8
hypogonadotropic hypogonadism 6 with or without anosmia

Mouse Phenotypes
skeleton phenotype
absent Meckel's cartilage
absent molars
abnormal mandible morphology
abnormal maxilla morphology
absent incus
abnormal calcaneum morphology
absent deltoid tuberosity
absent radius
abnormal limb bone morphology
abnormal skeleton development
Availability Mouse Genotype
Fgf8tm1.2Mrt/Fgf8tm1.3Mrt
Tg(Nes-cre)1Atp/0  (conditional)
Fgf8tm1.3Mrt/Fgf8tm1.4Mrt
Tg(Msx2-cre)5Rem/0  (conditional)
Fgf8tm1.3Mrt/Fgf8tm1.4Mrt
Tg(T-cre)1Lwd/0  (conditional)
*
Fgf8tm1Mrc/Fgf8tm2Mrc
Tg(Rarb-cre)1Mrc/0  (conditional)
Gt(ROSA)26Sortm1(Fgf8)Lma/Gt(ROSA)26Sor+
Tg(Msx2-cre)5Rem/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory