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Symbol
Name
ID

Fgf8
fibroblast growth factor 8
MGI:99604

Phenotype annotations related to hearing/vestibular/ear

Darker colors indicate more annotations

Human Phenotypes	Sensorineural hearing impairment
Disease(s) Associated with FGF8	Sensorineural hearing impairment
hypogonadotropic hypogonadism 6 with or without anosmia

Mouse Phenotypes		abnormal pillar cell differentiation	absent incus	abnormal cochlear sensory epithelium morphology	abnormal pillar cell morphology	absent pillar cells	abnormal patterning of the organ of Corti
Availability	Mouse Genotype	abnormal pillar cell differentiation	absent incus	abnormal cochlear sensory epithelium morphology	abnormal pillar cell morphology	absent pillar cells	abnormal patterning of the organ of Corti
	Fgf8^tm1.2Mrt/Fgf8^tm1.3Mrt Tg(Nes-cre)1Atp/0 (conditional)
	Fgf8^tm1.2Mrt/Fgf8^tm1.3Mrt Foxg1^tm1(cre)Skm/Foxg1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23