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Symbol
Name
ID

Hoxc13
homeobox C13
MGI:99560

Phenotype annotations related to integument

Darker colors indicate more annotations

Human Phenotypes	Absent eyelashes	Absent hair	Atrichia	Sparse hair	Abnormal sebaceous gland morphology	Abnormal sweat gland morphology	Concave nail	Nail dystrophy	Ectodermal dysplasia
Disease(s) Associated with HOXC13
ectodermal dysplasia 9

Mouse Phenotypes

increased keratinocyte proliferation

abnormal coat appearance

abnormal hair growth

alopecia

focal hair loss

hairless

loss of eyelid cilia

retarded hair growth

sparse hair

abnormal hair texture

brittle hair

abnormal hair shaft morphology

abnormal hair cuticle

deformed nails

toenail hyperkeratosis

thick hair follicle outer root sheath

enlarged hair follicles

hair follicle degeneration

abnormal vibrissa morphology

absent vibrissae

kinked vibrissae

abnormal hair cycle

abnormal epidermal layer morphology

disorganized suprabasal layer

thick epidermis

flaky skin

scaly skin

spontaneous skin ulceration

tight skin

Availability

Mouse Genotype

Hoxc13^N/Hoxc13^N

Hoxc13^tm1Mrc/Hoxc13^tm1Mrc

Hoxc13^tm2Mrc/Hoxc13^tm2Mrc

Hoxc13^tm3.1Mrc/Hoxc13^tm3.1Mrc

Hoxc13^tm3Mrc/Hoxc13^tm3Mrc

Hoxc13^N/Hoxc13⁺

Hoxc13^tm3.1Mrc/Hoxc13⁺

Hoxc13^tm3Mrc/Hoxc13⁺

Tg(Hoxc13)61B1Awg/0

Tg(Hoxc13)61U4Awg/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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