|
Symbol Name ID |
Piga
phosphatidylinositol glycan anchor biosynthesis, class A MGI:99461 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Prominent occiput |
Micrognathia |
Malar flattening |
Microcephaly |
Secondary microcephaly |
Increased head circumference |
Macrocephaly |
Metopic synostosis |
Large fontanelles |
Coarse facial features |
Gingival overgrowth |
High palate |
Downturned corners of mouth |
Triangular mouth |
Narrow mouth |
Microdontia |
Widely spaced teeth |
Pierre-Robin sequence |
Anteverted nares |
Depressed nasal bridge |
Conjunctival icterus |
Upslanted palpebral fissure |
| Disease(s) Associated with PIGA | ||||||||||||||||||||||
| multiple congenital anomalies-hypotonia-seizures syndrome 2 | ||||||||||||||||||||||
| paroxysmal nocturnal hemoglobinuria |
| Mouse Phenotypes | craniofacial phenotype |
abnormal craniofacial bone morphology |
abnormal facial morphology |
cleft upper lip |
cleft palate |
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| Availability | Mouse Genotype | |||||
| Pigatm1.1Tak/Piga+ | * | |||||
| H2az2Tg(Wnt1-cre)11Rth/H2az2+ Pigatm1Tak/Y (conditional) |
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| Pigatm1Bsl/Piga+ Tg(EIIa-cre)C5379Lmgd/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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