Symbol
Name
ID

Mc1r
melanocortin 1 receptor
MGI:99456

Phenotype annotations related to integument

Darker colors indicate more annotations

Human Phenotypes	Hypopigmentation of hair	Albinism	Red hair	Freckles in sun-exposed areas	Hypopigmentation of the skin
Disease(s) Associated with MC1R
oculocutaneous albinism type II

Mouse Phenotypes

abnormal keratinocyte apoptosis

decreased ear pigmentation

abnormal coat/hair pigmentation

darkened coat color

yellow coat color

abnormal hair follicle pheomelanosome pheomelanin content

abnormal hair follicle melanogenesis

abnormal pinna hair pigmentation

abnormal tail hair pigmentation

abnormal skin morphology

abnormal skin pigmentation

abnormal epidermal melanocyte morphology

decreased tail pigmentation

Availability

Mouse Genotype

Mc1r^e-J/Mc1r^e-J

Mc1r^E-so3J/Mc1r^E-so3J

Mc1r^E-so/Mc1r^E-so

Mc1r^e/Mc1r^e

Mc1r^m1Btlr/Mc1r^m1Btlr

Mc1r^mpc59H/Mc1r^mpc59H

Mc1r^taw/Mc1r^taw

Mc1r^{tm1.1(KOMP)Vlcg}/Mc1r^{tm1.1(KOMP)Vlcg}

Mc1r^E-so3J/Mc1r⁺

Mc1r^E-So4J/Mc1r⁺

Mc1r^E-so/Mc1r⁺

Mc1r^taw/Mc1r^e

Mc1r^tm1.1Mymi/Mc1r^tm1.1Mymi
Tg(Tyr-cre/ERT2)13Bos/0 (conditional)

Mc1r^tm1.1Mymi/Mc1r^tm1.1Mymi
Tg(CMV-cre)1Cgn/0 (conditional)

Mc1r^tm1.1Mymi/Mc1r^tm1.1Mymi
Tg(CMV-cre)1Cgn/0
Tg(Dct-lacZ)#Ove/0 (conditional)

Mc1r^tm1.1Mymi/Mc1r^tm1.1Mymi
Tg(Dct-lacZ)#Ove/0
Tg(Tyr-cre/ERT2)13Bos/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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