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Symbol
Name
ID

Wnt7a
wingless-type MMTV integration site family, member 7A
MGI:98961

Phenotype annotations related to skeleton

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Calvarial skull defect

Decreased calvarial ossification

Micrognathia

Short neck

Bowing of the long bones

Radial bowing

Femoral bowing

Aplasia/Hypoplasia of the 5th finger

Postaxial hand polydactyly

Abnormal finger flexion crease

Aplasia/Hypoplasia of the phalanges of the hand

Aplasia/Hypoplasia of fingers

Finger aplasia

Ulnar deviation of finger

Aplasia/Hypoplasia of the phalanges of the toes

Foot oligodactyly

Toe syndactyly

Clinodactyly

Finger syndactyly

Aplasia/hypoplasia of the femur

Aplasia/Hypoplasia of the fibula

Fibular aplasia

Aplasia/Hypoplasia of metatarsal bones

Abnormal tibia morphology

Aplasia/Hypoplasia of the tarsal bones

Short foot

Patellar aplasia

Hypoplasia of the radius

Humeroradial synostosis

Aplasia/Hypoplasia of the ulna

Aplasia of the ulna

Aplasia/Hypoplasia involving the metacarpal bones

Aplasia/Hypoplasia involving the carpal bones

Carpal bone aplasia

Ectrodactyly

Split hand

Hip dislocation

Congenital hip dislocation

Elbow ankylosis

Elbow flexion contracture

Aplasia/hypoplasia of the extremities

Micromelia

Phocomelia

Congenital pseudoarthrosis of the clavicle

Hypoplastic iliac wing

Aplasia/Hypoplasia of the pubic bone

Aplastic pubic bone

Aplasia/Hypoplasia involving the pelvis

Hypoplastic pelvis

Broad clavicles

Broad ribs

Barrel-shaped chest

Pectus carinatum

Prominent sternum

Aplasia/Hypoplasia of the sacrum

Pilonidal sinus

Hemivertebrae

Disease(s) Associated with WNT7A

Fuhrmann syndrome

Schinzel type phocomelia

Mouse Phenotypes		skeleton phenotype	fused phalanges	abnormal humerus morphology	short humerus	abnormal ulna morphology	absent ulna	short fibula	scapular bone foramen	increased rib number	decreased presacral vertebrae number
Availability	Mouse Genotype	skeleton phenotype	fused phalanges	abnormal humerus morphology	short humerus	abnormal ulna morphology	absent ulna	short fibula	scapular bone foramen	increased rib number	decreased presacral vertebrae number
	Wnt7a^px-2J/Wnt7a^px-2J
	Wnt7a^px-r/Wnt7a^px-r	*
	Wnt7a^px/Wnt7a^px
	Wnt7a^tm1Amc/Wnt7a^tm1Amc

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23