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Symbol
Name
ID

Trp53
transformation related protein 53
MGI:98834

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes	Muscle weakness	Generalized muscle weakness	Myopathy	Rhabdomyosarcoma
Disease(s) Associated with TP53	Muscle weakness	Generalized muscle weakness	Myopathy	Rhabdomyosarcoma
Graves' disease
Leber hereditary optic neuropathy
Li-Fraumeni syndrome
mismatch repair cancer syndrome
multiple myeloma

Mouse Phenotypes		decreased skeletal muscle mass	increased leiomyosarcoma incidence	increased rhabdomyosarcoma incidence	muscular atrophy
Availability	Mouse Genotype	decreased skeletal muscle mass	increased leiomyosarcoma incidence	increased rhabdomyosarcoma incidence	muscular atrophy
	Trp53^tm1.1Thst/Trp53^tm1.1Thst
	Trp53^tm1Brd/Trp53^tm1Brd
	Trp53^tm1Tyj/Trp53^tm1Tyj
	Trp53^tm1Ldo/Trp53⁺
	Trp53^tm1Tyj/Trp53⁺
	Tg(Trp53A135V)L3Ber/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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