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Symbol
Name
ID

Tgfbr2
transforming growth factor, beta receptor II
MGI:98729

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes	Joint contracture of the hand	Flexion contracture	Camptodactyly	Hypertonia	Hypotonia	Decreased muscle mass	Rhabdomyosarcoma
Disease(s) Associated with TGFBR2	Joint contracture of the hand	Flexion contracture	Camptodactyly	Hypertonia	Hypotonia	Decreased muscle mass	Rhabdomyosarcoma
Loeys-Dietz syndrome 2
Lynch syndrome
Marfan syndrome
mismatch repair cancer syndrome

Mouse Phenotypes		dilated cardiomyopathy	decreased cardiac muscle contractility	abnormal vasodilation	abnormal soft palate muscle morphology	small levator veli palatini muscle	small tensor veli palatini muscle	abnormal skeletal muscle fiber morphology	centrally nucleated skeletal muscle fibers
Availability	Mouse Genotype	dilated cardiomyopathy	decreased cardiac muscle contractility	abnormal vasodilation	abnormal soft palate muscle morphology	small levator veli palatini muscle	small tensor veli palatini muscle	abnormal skeletal muscle fiber morphology	centrally nucleated skeletal muscle fibers
	Tgfbr2^tm1.2Hlm/Tgfbr2^tm1.2Hlm H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)
	Tgfbr2^tm1.2Hlm/Tgfbr2^tm1.2Hlm Tg(KRT14-cre)52Smr/0 (conditional)
	Tgfbr2^tm1.2Hlm/Tgfbr2^tm1.2Hlm A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺ (conditional)
	Tgfbr2^tm1Karl/Tgfbr2^tm1Karl H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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