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Symbol
Name
ID

Tgfbr1
transforming growth factor, beta receptor I
MGI:98728

Phenotype annotations related to integument

Darker colors indicate more annotations

Human Phenotypes	Adenoma sebaceum	Breast carcinoma	Striae distensae	Soft skin	Dermal translucency	Neoplasm of the skin	Basal cell carcinoma	Self-healing squamous epithelioma
Disease(s) Associated with TGFBR1	Adenoma sebaceum	Breast carcinoma	Striae distensae	Soft skin	Dermal translucency	Neoplasm of the skin	Basal cell carcinoma	Self-healing squamous epithelioma
Loeys-Dietz syndrome 1
Lynch syndrome

Mouse Phenotypes		decreased subcutaneous adipose tissue amount	sparse hair	abnormal dermal layer morphology	thick dermal layer	thin epidermis	abnormal skin condition	thick skin	abnormal skin development
Availability	Mouse Genotype	decreased subcutaneous adipose tissue amount	sparse hair	abnormal dermal layer morphology	thick dermal layer	thin epidermis	abnormal skin condition	thick skin	abnormal skin development
	Gt(ROSA)26Sor^{tm1(Tgfbr1*)Crm}/Gt(ROSA)26Sor⁺ Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0 (conditional)
	Tgfbr1^tm1Karl/Tgfbr1^tm1.1Karl Tg(GATA5-cre)1Krc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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