Symbol
Name
ID

Tgfb3
transforming growth factor, beta 3
MGI:98727

Phenotype annotations related to craniofacial

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes

Brachycephaly

Dolichocephaly

Retrognathia

Broad face

Long face

Midface retrusion

Smooth philtrum

Tented upper lip vermilion

Bifid uvula

Cleft soft palate

Cleft palate

High palate

Overhanging nasal tip

Prominent nasal bridge

Long palpebral fissure

Downslanted palpebral fissures

Disease(s) Associated with TGFB3

Loeys-Dietz syndrome 5

Mouse Phenotypes		abnormal secondary palate development	persistence of medial edge epithelium during palatal shelf fusion	cleft secondary palate	cleft palate	anterior cleft palate	complete cleft palate
Availability	Mouse Genotype	abnormal secondary palate development		cleft secondary palate	cleft palate	anterior cleft palate	complete cleft palate
	Tgfb3^tm1(cre)Vk/Tgfb3^tm1(cre)Vk
	Tgfb3^tm1Doe/Tgfb3^tm1Doe				!	!
	Tgfb3^tm1Jhg/Tgfb3^tm1Jhg
	Tgfb3^tm1Moaz/Tgfb3^tm1.1Moaz Tg(EIIa-cre)C5379Lmgd/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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