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Symbol
Name
ID
Tcf4
transcription factor 4
MGI:98506
Phenotype annotations related to behavior/neurological
Darker colors indicate more annotations
Human Phenotypes
Feeding difficulties
Echolalia
Mutism
Aggressive behavior
Self-injurious behavior
Happy demeanor
Autistic behavior
Sleep disturbance
Sleep apnea
Disease(s) Associated with TCF4
Pitt-Hopkins syndrome

Mouse Phenotypes
abnormal associative learning
impaired contextual conditioning behavior
impaired cued conditioning behavior
abnormal habituation to a new environment
impaired spatial learning
decreased anxiety-related response
increased thigmotaxis
decreased startle reflex
hyperactivity
Availability Mouse Genotype
Tg(Thy1-Tcf4)1Mjro/0
Tcf4em1Bdph/?
Tcf4tm1Hmb/Tcf4+
Tmem163Tg(ACTB-cre)2Mrt/Tmem163+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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Funding Information
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory