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Symbol Name ID |
Tcf4
transcription factor 4 MGI:98506 |
| Darker colors indicate more annotations |
| Human Phenotypes | Abdominal pain |
Feeding difficulties |
Eye movement-induced pain |
Depression |
Atypical behavior |
Happy demeanor |
Autistic behavior |
Aggressive behavior |
Attention deficit hyperactivity disorder |
Motor stereotypy |
Self-injurious behavior |
Fatigue |
| Disease(s) Associated with TCF4 | ||||||||||||
| Fuchs' endothelial dystrophy | ||||||||||||
| Lynch syndrome | ||||||||||||
| Pitt-Hopkins syndrome |
| Mouse Phenotypes | abnormal associative learning |
impaired contextual conditioning behavior |
impaired cued conditioning behavior |
abnormal habituation to a new environment |
impaired spatial learning |
abnormal long-term spatial reference memory |
decreased anxiety-related response |
increased thigmotaxis |
increased grooming behavior |
decreased startle reflex |
increased startle reflex |
impaired balance |
decreased grip strength |
abnormal gait |
increased locomotor activity |
social withdrawal |
decreased vocalization |
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| Availability | Mouse Genotype | |||||||||||||||||
| Tcf4tm1Zhu/Tcf4+ | ||||||||||||||||||
| Tg(Thy1-Tcf4)1Mjro/0 | ||||||||||||||||||
| Tcf4em1Bdph/? | ||||||||||||||||||
| Tcf4tm1Hmb/Tcf4+ Tmem163Tg(ACTB-cre)2Mrt/Tmem163+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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