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Symbol Name ID |
Spp1
secreted phosphoprotein 1 MGI:98389 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Interphalangeal joint erosions |
Swan neck-like deformities of the fingers |
Joint swelling |
Joint stiffness |
Bone pain |
Pathologic fracture |
Vertebral compression fracture |
Back pain |
Osteopenia |
Rheumatoid arthritis |
Polyarticular arthritis |
Digital flexor tenosynovitis |
| Disease(s) Associated with SPP1 | ||||||||||||
| multiple myeloma | ||||||||||||
| pancreatic cancer | ||||||||||||
| rheumatoid arthritis |
| Mouse Phenotypes | skeleton phenotype |
abnormal osteoblast physiology |
decreased osteoclast cell number |
increased osteoclast cell number |
abnormal osteoclast physiology |
abnormal long bone metaphysis morphology |
increased bone mineral density of lumbar vertebrae |
increased bone mineral density of presacral vertebrae |
increased bone mineral density |
increased trabecular bone thickness |
abnormal bone mineralization |
decreased bone resorption |
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| Availability | Mouse Genotype | ||||||||||||
| Spp1tm1.1Dhd/Spp1tm1.1Dhd | |||||||||||||
| Spp1tm1Blh/Spp1tm1Blh | |||||||||||||
| Spp1tm1Rit/Spp1tm1Rit | * | ||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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