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Symbol
Name
ID

Sos1
SOS Ras/Rac guanine nucleotide exchange factor 1
MGI:98354

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes	Aplasia/Hypoplasia of the abdominal wall musculature	Hypotonia	Muscle weakness
Disease(s) Associated with SOS1
Noonan syndrome

Mouse Phenotypes		abnormal myocardial fiber morphology	increased myocardial fiber size	myocardial fiber degeneration	abnormal myocardial trabeculae morphology	heart left ventricle hypertrophy	heart right ventricle hypertrophy	abnormal fetal cardiomyocyte proliferation	increased cardiomyocyte apoptosis
Availability	Mouse Genotype	abnormal myocardial fiber morphology	increased myocardial fiber size	myocardial fiber degeneration	abnormal myocardial trabeculae morphology	heart left ventricle hypertrophy	heart right ventricle hypertrophy	abnormal fetal cardiomyocyte proliferation	increased cardiomyocyte apoptosis
	Sos1^tm1.2Rak/Sos1^tm1.2Rak
	Sos1^tm1Dlb/Sos1^tm1Dlb
	Sos1^tm1.2Rak/Sos1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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