Symbol
Name
ID

Sod1
superoxide dismutase 1, soluble
MGI:98351

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Decreased level of 1,5 anhydroglucitol in serum	Hyperglycemia	Diabetes mellitus	Type II diabetes mellitus	Hyperinsulinemia	Insulin resistance	Ketoacidosis	Edema	Pulmonary edema
Disease(s) Associated with SOD1	Decreased level of 1,5 anhydroglucitol in serum	Hyperglycemia	Diabetes mellitus	Type II diabetes mellitus	Hyperinsulinemia	Insulin resistance	Ketoacidosis	Edema	Pulmonary edema
Down syndrome
newborn respiratory distress syndrome
retinitis pigmentosa
type 1 diabetes mellitus
type 2 diabetes mellitus

Mouse Phenotypes

homeostasis/metabolism phenotype

increased myocardial infarct size

impaired adaptive thermogenesis

increased circulating glucose level

abnormal circulating hormone level

increased circulating corticosterone level

suppressed circulating follicle stimulating hormone level

decreased circulating luteinizing hormone level

decreased circulating insulin level

decreased circulating leptin level

decreased circulating triiodothyronine level

increased circulating ketone body level

increased circulating interleukin-6 level

increased circulating tumor necrosis factor level

abnormal energy expenditure

abnormal enzyme/coenzyme level

abnormal gas homeostasis

increased oxygen consumption

decreased respiratory quotient

abnormal glucose homeostasis

abnormal lipid homeostasis

abnormal glycerol level

enhanced lipolysis

increased susceptibility to xenobiotic induced morbidity/mortality

Availability

Mouse Genotype

Sod1^tm1Dkd/Sod1^tm1Dkd

Sod1^tm1Leb/Sod1^tm1Leb

Sod1^tm1Ysh/Sod1^tm1Ysh

Tg(Sod1*G86R)M1Jwg/0

Sod1^tm1Svb/Sod1^tm1Svb
Tg(ACTA1-cre)79Jme/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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