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Symbol
Name
ID
Rb1
RB transcriptional corepressor 1
MGI:97874
Phenotype annotations related to cellular
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
cellular phenotype
abnormal chromosome morphology
aneuploidy
polyploidy
abnormal cell cycle
abnormal cell cycle checkpoint function
abnormal mitosis
increased mitotic index
increased lens fiber apoptosis
increased neuron apoptosis
abnormal retina apoptosis
decreased retina apoptosis
increased retina apoptosis
decreased apoptosis
increased apoptosis
abnormal cell differentiation
abnormal macrophage differentiation
abnormal neuron differentiation
abnormal cell proliferation
abnormal enterocyte proliferation
increased fibroblast proliferation
abnormal neuronal precursor proliferation
abnormal organ of Corti supporting cell proliferation
increased cell proliferation
Availability Mouse Genotype
Rb1tm1.1Jyjw/Rb1tm1.1Jyjw
Rb1tm1Brd/Rb1tm1Brd
Rb1tm1Dwg/Rb1tm1Dwg
Rb1tm1Fad/Rb1tm1Fad
Rb1tm1Jyjw/Rb1tm1Jyjw
Rb1tm1Mlh/Rb1tm1Mlh
Rb1tm1Tyj/Rb1tm1Tyj
Rb1tm1Tyj/Rb1tm1Tyj
Tg(Rb1)1Blg/0
Rb1tm2.1Fad/Rb1tm2.1Fad *
Rb1tm2Mlh/Rb1tm2Mlh
Rb1tm1.1Jyjw/Rb1+
Rb1tm1Jyjw/Rb1+
Rb1tm2Brn/Rb1tm2Brn
Tg(Col1a1-cre)1Bek/0  (conditional)
Rb1tm2Brn/Rb1tm2Brn
Tg(Pou4f3-cre)1Devet/0  (conditional)
Rb1tm2Brn/Rb1tm2Brn
Tg(En2-cre)22Alj/0  (conditional)
Rb1tm2Brn/Rb1tm2Brn
Tg(Cyp1a1-cre)1Dwi/0  (conditional)
Rb1tm3Tyj/Rb1tm3Tyj
Tg(Pax6-cre,GFP)2Pgr/0  (conditional)
Rb1tm3Tyj/Rb1tm3Tyj
Tg(Nes-cre)1Atp/0  (conditional)
Rb1tm3Tyj/Rb1tm3Tyj  (conditional)
Rb1tm3Tyj/Rb1tm3.1Tyj
Tg(Nes-cre)1Atp/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory