Symbol
Name
ID

Ptpn2
protein tyrosine phosphatase, non-receptor type 2
MGI:97806

Phenotype annotations related to skeleton

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

skeleton phenotype

abnormal osteoclast differentiation

abnormal osteoclast physiology

decreased diameter of femur

short femur

abnormal skeleton morphology

abnormal long bone morphology

abnormal long bone epiphyseal ossification zone morphology

decreased long bone epiphyseal plate size

abnormal bone structure

decreased bone mineral content

decreased bone mineral density

increased bone mineral density

decreased trabecular bone volume

increased trabecular bone volume

abnormal bone trabecula morphology

decreased bone trabecula number

increased bone trabecula number

abnormal ossification involved in bone maturation

increased bone resorption

Availability

Mouse Genotype

Ptpn2^tm1Mtr/Ptpn2^tm1Mtr

Ptpn2^tm2.1Ttig/Ptpn2^tm2.1Ttig

Ptpn2^tm1.1Kry/Ptpn2^tm1.1Kry
Tg(Col1a1-cre)1Kry/0 (conditional)

Ptpn2^tm1.1Ttig/Ptpn2^tm1.1Ttig
Tg(Nes-cre)1Kln/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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