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Symbol
Name
ID
Pomc
pro-opiomelanocortin-alpha
MGI:97742
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abdominal pain
Episodic abdominal pain
Low back pain
Depression
Arthralgia
Chest pain
Myalgia
Disease(s) Associated with POMC
familial mediterranean fever

Mouse Phenotypes
behavior/neurological phenotype
abnormal behavior
abnormal alcohol consumption
increased alcohol consumption
abnormal behavioral response to addictive substance
hyperactivity elicited by ethanol administration
impaired conditioned place preference behavior
abnormal operant conditioning behavior
decreased compensatory feeding amount
decreased food intake
increased food intake
polyphagia
increased aggression towards mice
decreased locomotor activity
abnormal touch/ nociception
Availability Mouse Genotype
Pomctm1.1Kgm/Pomctm1.1Kgm
Pomctm1Low/Pomctm1Low *
Pomctm1Sora/Pomctm1Sora
Pomctm2.1Low/Pomctm2.1Low *
Pomctm2Low/Pomctm2Low
Pomctm2Ute/Pomctm2Ute
Pomctm2Low/Pomctm2Low
Tg(CAG-cre/Esr1*)5Amc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory