Symbol
Name
ID

Pmp22
peripheral myelin protein 22
MGI:97631

Phenotype annotations related to behavior/neurological

Darker colors indicate more annotations

Human Phenotypes	Vocal cord paralysis	Abnormality of the voice	Shoulder pain
Disease(s) Associated with PMP22	Vocal cord paralysis	Abnormality of the voice	Shoulder pain
Charcot-Marie-Tooth disease type 1A
hereditary neuropathy with liability to pressure palsies

Mouse Phenotypes

abnormal motor capabilities/coordination/movement

impaired righting response

limb grasping

tremors

abnormal motor coordination/balance

ataxia

impaired coordination

decreased grip strength

weakness

abnormal gait

decreased locomotor activity

forelimb paralysis

hindlimb paralysis

spasticity

abnormal sexual interaction

seizures

convulsive seizures

Availability

Mouse Genotype

Pmp22^Mhdatre002/Pmp22^Mhdatre002

Pmp22^tm1Lnot/Pmp22^tm1Lnot

Pmp22^tm1Ueli/Pmp22^tm1Ueli

Pmp22^Tr-J/Pmp22^Tr-J

Pmp22^Tr-Ncnp/Pmp22^Tr-Ncnp

Pmp22^Tr/Pmp22^Tr

Pmp22^M1247Lja/Pmp22⁺

Pmp22^tm1Lnot/Pmp22⁺

Pmp22^tm1Ueli/Pmp22⁺

Pmp22^Tr-1H/Pmp22⁺

Pmp22^Tr-2H/Pmp22⁺

Pmp22^Tr-2J/Pmp22⁺

Pmp22^Tr-3H/Pmp22⁺

Pmp22^Tr-J/Pmp22⁺

Pmp22^Tr-Ncnp/Pmp22⁺

Pmp22^Tr/Pmp22⁺

Tg(Pmp22)My41Clh/0

Tg(PMP22-tTA)JY13Clh/0
Tg(tetO/CMV-Pmp22)JP18Clh/0

Pmp22^Tr-J/?

Pmp22^Tr/?

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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