|
Symbol Name ID |
Otx2
orthodenticle homeobox 2 MGI:97451 |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Cleft palate |
Depressed nasal ridge |
| Disease(s) Associated with OTX2 | ||
| panhypopituitarism | ||
| syndromic microphthalmia 5 |
| Mouse Phenotypes | abnormal craniofacial morphology |
abnormal cranium morphology |
abnormal basisphenoid bone morphology |
basisphenoid bone foramen |
abnormal Meckel's cartilage morphology |
small cranium |
frontal bone foramen |
abnormal alisphenoid bone morphology |
absent orbitosphenoid bone |
abnormal presphenoid bone morphology |
abnormal pterygoid bone morphology |
abnormal temporal bone tympanic part morphology |
abnormal mandible morphology |
absent mandibular coronoid process |
absent mandible |
micrognathia |
abnormal incus morphology |
abnormal malleus morphology |
abnormal maxillary prominence morphology |
abnormal nasal capsule morphology |
absent nasal capsule |
absent nasal placodes |
abnormal first pharyngeal arch morphology |
absent pharyngeal arches |
abnormal facial morphology |
abnormal palate morphology |
absent tongue |
abnormal nasal cavity morphology |
abnormal nasal septum morphology |
abnormal vomeronasal organ morphology |
absent vomeronasal organ |
absent nasal septum |
abnormal olfactory epithelium morphology |
abnormal snout morphology |
short snout |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||
| Otx2tm1Pas/Otx2tm1Pas | ||||||||||||||||||||||||||||||||||||
| Otx2tm3Tlam/Otx2tm3Tlam | ||||||||||||||||||||||||||||||||||||
| Otx2tm9Asim/Otx2tm9Asim | ||||||||||||||||||||||||||||||||||||
| Otx2tm1Pas/Otx2tm2Asim | ||||||||||||||||||||||||||||||||||||
| Otx2tm1Sia/Otx2+ | ! | |||||||||||||||||||||||||||||||||||
| Otx2tm1Sia/Otx2tm4Sia | ||||||||||||||||||||||||||||||||||||
| H2az2Tg(Wnt1-cre)11Rth/H2az2+ Tg(CAG-Otx2,-EGFP)1Eno/? (conditional) |
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| Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam (conditional) | ||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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